The fiery heap came to rest at about 2:37 a.m. in the deserted parking lot of a repair and towing company about a mile or two from the airport where it had been preparing to land, Joe Rotterdam, the manager of airport operations with the Lucas County Port Authority, said during a news conference.
The plane hit multiple unoccupied vehicles around the shop, which is within a half-mile from the Ohio Turnpike.
"The aircraft struck multiple unoccupied vehicles on the ground and a significant fire resulted from that impact," Rotterdam told reporters. "Because of those vehicles, there was a very significant fire."
The two people who died were aboard the Convair 440, Toledo-Lucas County Port Authority spokeswoman Kayla Lewandowski told the Associated Press. Rotterdam said officials couldn't yet confirm whether any distress call was made from the aircraft.
Port Authority officials said they believe the wrecked plane was carrying auto parts on an "unscheduled" cargo operation. Rotterdam added, however, that a lot of cargo flights at the airport are unscheduled.
Report: Plane crashes in Ohio after leaving Millington airport
The National Transportation Safety Board said on Twitter it was investigating the crash and that it involved a Convair 440 aircraft — a turboprop plane.
The plane is believed to have originally traveled from Laredo, Texas, to Millington, Tenn., before making the flight to the Toledo area, WTOL reported. Flight records obtained by the television station show the aircraft was supposed to have landed at about the same time as the plane crash occurred.
Video: Cargo plane bursts into flames at Toledo airport
Multiple agencies responded to the scene, with teams working to secure wreckage scattered over what officials described as a large debris field.
UPDATE: 2 Pilots Dead After Toledo Deadly Plane Crash
By mid-morning, no flames were visible as firefighters occasionally sprayed water on the smoldering wreckage, according to the AP. The debris appeared to be contained to the auto business, where at least one trailer was mangled and burned.
Rotterdam said it's not clear if there is a so-called black box with recorded data about the flight. No further details were immediately available about the people who died or the plane's owner.
The Federal Aviation Administration and the Ohio State Highway Patrol were helping with the investigation. The Toledo Express Airport remained open, and flights were not affected by the incident.
2 dead after cargo plane crashes, burns near Toledo airport
TOLEDO, Ohio (AP) Authorities say two people are dead after a cargo plane on a flight from Texas crashed early Wednesday as it approached an Ohio airport and burst into flames as it hit several unoccupied vehicles.
Crashed Convair came down about 1km from runway
No other injuries were reported from the crash early Wednesday at an auto repair shop just east of the Toledo Express Airport.
Toledo-Lucas County Port Authority spokeswoman Kayla Lewandowski says the two people who died were aboard the Convair 440.
The port authoritys manager of airline affairs, Joe Rotterdam, says officials cant yet confirm whether any distress call was made from the aircraft.
Convair CV-440 Freighter Crashes in Ohio
Rotterdam says officials believe the plane had traveled from Laredo, and stopped outside Memphis, Tenn., on Tuesday before heading to Ohio.
They said no further details were immediately available about the people who died or the planes owner.